Title Elektrinio verpimo būdu formuojamų neaustinių medžiagų su biomedicininės paskirties funkcinėmis dalelėmis formavimas ir tyrimas /
Translation of Title The formation and analysis of electrospun nonwoven materials with biomedical functional particles.
Authors Bolskis, Evaldas
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Pages 67
Keywords [eng] electrospinning ; non-woven material ; nano-microfibers ; hydroxyapatite particles ; silver particles
Abstract [eng] Electrospinning method is used for forming a nonwoven material from nano-microfibers using different polymer solutions or melt. Due electrostatic forces created during electrospinning process from polymer solution are formed nonwoven material from nano-microfibers. Electrospun nonwoven material from nano-microfibers, have attracted much attention due to unique properties such as high specific surface area, small fibers diameter. Due to those propertie these materials are widely use in filtration, catalysis, protective or smart clothing, optical devices, membranes, sensors, for medical purposes as wound healing dressings, tissue engineering (scaffolds for cells), and as a drug delivery system. The aim of this study is to form and analyse electrospun nonwoven materials from nano –microfibers, with biomedical functional hydroxyapatite(HAp) and silver(AgNp) particles. The object of investigation ̶ methyl methacrylate and methacrylic acid (2:1) (MMA/MA) copolymer – hydrophobic, biocompatible, biodegradable copolymer and poly(vinyl alcohol) ̶ hydrophilic, biomedical purpose, water-soluble polymer. During this study was estimated that preparation methods of HAp particles have influence on diameter of electrospun PVA nano-microfibers. The best concentration of MMA/MA polymer in ethanol is 5 %, at this concentration were electrospun fibers with diameter to 200 nm (75 % amount of MMA/MA fibers). Insertion of functional HAp, AgNp particles in MMA/MA solution have influence of electrospun nonwoven material structure and properties. Electrospun nonwoven material with AgNp showed antimicrobial properties. Electrospun nonwoven material with functional HAp and AgNp have higher wetting angle and biodegradable faster then nonwoven material from pure MMA/MA nano-microfibers.
Dissertation Institution Kauno technologijos universitetas.
Type Master thesis
Language Lithuanian
Publication date 2017