Title Endogenous motion of liver correlates to the severity of portal hypertension :
Authors Gelman, Sigita ; Sakalauskas, Andrius ; Zykus, Romanas ; Pranculis, Andrius ; Jurkonis, Rytis ; Kuliavienė, Irma ; Lukoševičius, Arūnas ; Kupčinskas, Limas ; Kupčinskas, Juozas
DOI 10.3748/wjg.v26.i38.5836
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Is Part of World journal of gastroenterology.. Pleasanton, CA : Baishideng publishing group. 2020, vol. 26, no. 38, p. 5836-5848.. ISSN 1007-9327. eISSN 2219-2840
Keywords [eng] hypertension, portal ; liver cirrhosis ; portal vein ; portal pressure ; elasticity imaging techniques
Abstract [eng] Degree of portal hypertension (PH) is the most important prognostic factor for the decompensation of liver cirrhosis and death, therefore adequate care for patients with liver cirrhosis requires timely detection and evaluation of the presence of clinically significant PH (CSPH) and severe PH (SPH). As the most accurate method for the assessment of PH is an invasive direct measurement of hepatic venous pressure gradient (HVPG), the search for non-invasive methods to diagnose these conditions is actively ongoing. AIM To evaluate the feasibility of parameters of endogenously induced displacements and strain of liver to assess degree of PH. METHODS Of 36 patients with liver cirrhosis and measured HVPG were included in the casecontrol study. Endogenous motion of the liver was characterized by derived parameters of region average tissue displacement signal (dantero, dretro, dRMS) and results of endogenous tissue strain imaging using specific radiofrequency signal processing algorithm. Average endogenous strain μ and standard deviation σ of strain were assessed in the regions of interest (ROI) (1 cm × 1 cm and 2 cm × 2 cm in size) and different frequency subbands of endogenous motion (0-10 Hz and 10- 20 Hz). RESULTS Four parameters showed statistically significant (P < 0.05) correlation with HVPG measurement. The strongest correlation was obtained for the standard deviation of strain (estimated at 0-10 Hz and 2 cm × 2 cm ROI size). [...].
Published Pleasanton, CA : Baishideng publishing group
Type Journal article
Language English
Publication date 2020
CC license CC license description