Title Identification of predictors of inhospital postreperfusion mode of death in patients with acute ST-elevation myocardial infarction /
Another Title Poreperfuzinių mirčių stacionariniu laikotarpiu patomechanizmo prognostinių kriterijų paieška sergantiesiems ūminiu miokardo infarktu su ST pakilimu.
Authors Vaicekavičius, Edvardas ; Navickas, Ramūnas ; Survila, Leonas ; Štuikys, Vytautas ; Janavičius, Arnoldas ; Valančius, Kęstutis
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Is Part of Medicina.. Kaunas : Kauno medicinos universitetas. 2010, t. 46, Nr. 2, p. 104-112.. ISSN 1010-660X
Keywords [eng] Percutaneous coronary interventions ; Myocardial reperfusion therapy ; Postreperfusion inhospital death ; Risk stratification of postreperfusion complications
Abstract [eng] Objectives. The aim of this study was to identify the predictors of the postreperfusion mode of death using the distinctions in clinical characteristics of patients who died and survived after reperfusion therapy, treated due to ST-elevation myocardial infarction (STEMI). Material and methods. This consecutive study has involved 36 patients: 18 patients who died from progressive heart failure (PHF) (group 1, n=13) or from cardiac rupture (CR) (group 2, n=5) after primary coronary intervention. The control group consisted of 18 randomly selected patients who survived inhospital period (group 3). The initial and postreperfusion heart rate (HR), systolic and diastolic arterial pressures (SAP and DAP), maximal ST elevation (max ST­) and depression (max ST¯), ST score, TIMI flow grade, coronary score (CS), and their perireperfusion changes were assessed for each patient. The complex prognostic predictors – TIMI Risk Score and TIMI Risk Index – were also assessed. The data analysis was performed by standard statistical and machine learning approach methods. Results. The comparison of three patients’ groups according to simple ECG or circulatory characteristics showed that more significant differences were seen in postreperfusion characteristics or their perireperfusion changes. Herewith, the major part of significantly different characteristics (baseline SAP, DAP, and HR, postreperfusion SAP, DAP, ST score, and TIMI flow grade, resolution of ST score) was observed comparing both the groups of dead patients with survivors (control group). The differences in the complex predictors (TIMI Risk Score and TIMI Risk Index) were similar. However, the smallest number of significantly different characteristics was seen comparing both the groups of dead patients. [...].
Published Kaunas : Kauno medicinos universitetas
Type Journal article
Language English
Publication date 2010