Title Ultrasound spectra relation with microbubble’s sonodestruction and molecules sonotransfer /
Authors Jurkonis, Rytis ; Ruzgys, Paulius ; Šatkauskas, Saulius ; Lukoševičius, Arūnas ; Venslauskas, Mindaugas
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Is Part of Biomedical engineering 2014: proceedings of the 18th international conference, 27-28 November, 2014, Kaunas, Lithuania / Kaunas University of Technology Biomedical Engineering Institute.. Kaunas : Technologija. 2014, p. 63-70.. ISSN 2029-3380
Keywords [eng] sonoporation ; ultrasound ; microbubbles ; drug delivery ; spectral analysis
Abstract [eng] The dependence of sonotransfer efficiency of anticancer drug etidium bromide into the cells upon microbubbles (MB) sonodestruction rate was studied. The analysis of ultrasound (US) attenuation and scattering spectra, MB sonodestruction rate as well as sonotransfer efficiency implies the following:1) The MB sonodestruction dynamics is strongly dependent on US strength and pulse duration; 2) Sonotransfer efficiency show the consistent pattern with MB sonodestruction dynamics; 3) The correlation of the MB sonodestruction intensity with the sonotransfer efficiency is dependent on the characteristics of applied US as well on type of used MB.
Published Kaunas : Technologija
Type Conference paper
Language English
Publication date 2014