| Abstract [eng] |
In cases of brain injuries, brain and central nervous system infections, infections after the intracranial surgeries and other cases, where the intracranial pressure measurement is applied where possible, in order to reduce the health damage and to maintain a high quality of life, and to increase the likelihood of survival in the most severe cases, it is important to increase the accuracy of the non-invasive intracranial pressure measurement, which is based on the peculiarities of arterial blood flow in the human ophthalmic artery. On this basis, the aim of this research was, by using the numerical method, to determine the dependencies of the blood flow in the patient specific, compliant ophthalmic artery on the added external pressure, which is applied during the non-invasive intracranial pressure measurement. In order to achieve the aim of the research, a method was created that allows the modeling of the patient specific ophthalmic artery using the most advanced artery wall material model, by forming a vector field, which models the fibrous structure, which is the intrinsic property of the arterial wall. During the research, the dependence of the arterial blood flow on the intracranial pressure, measurement distance and the added external pressure was determined, as well as the dependence of the non-invasive intracranial pressure measurement systematic deviation on the current intracranial pressure and measurement distance in terms of the differences in the cross-sectional area and the differences in the mean blood velocity between the measurement locations. The established blood flow dependencies of the ophthalmic artery provide the basis for the improvement of the non-invasive intracranial pressure measurement accuracy, and the developed numerical model can further be used to address the interaction between the elastic material and the fluid flow. |
