| Title |
Synthesis and biological activity of 3-[phenyl(1,3-thiazol-2-yl)-amino]propanoic acids and their derivatives / |
| Authors |
Mickevičius, Vytautas ; Voskienė, Aušra ; Jonuškienė, Ilona ; Kolosej, Ramūnė ; Šiugždaitė, Jūratė ; Venskutonis, Petras Rimantas ; Kazernavičiūtė, Rita ; Brazienė, Zita ; Jakienė, Elena |
| DOI |
10.3390/molecules181215000 |
| Full Text |
|
| Is Part of |
Molecules.. Basel : MDPI. 2013, vol. 18, iss. 12, p. 15000-15018.. ISSN 1420-3049 |
| Keywords [eng] |
N-phenyl-N-thiocarbamoyl-β-alanine ; hantzsch synthesis ; thiazole ; hydrazone ; biological activity |
| Abstract [eng] |
New N,N-disubstituted β-amino acids and their derivatives with thiazole, aromatic, and heterocyclic substituents were synthesized from N-phenyl-N-thiocarbamoyl-β-alanine by the Hantzsch method; derivatives with hydrazone fragments were also obtained. Some of the synthesized compounds exhibited discrete antimicrobial activity, and 3-[(4-oxo-4,5-dihydro-1,3-thiazol-2-yl)(phenyl)amino]propanoic acid was found to promote rapeseed growth and to increase seed yield and oil content. |
| Published |
Basel : MDPI |
| Type |
Journal article |
| Language |
English |
| Publication date |
2013 |
| CC license |
|
