| Title |
Nanonešiklių įtakos raudonųjų dobilų ekstrakto komponentų skvarbai į odą ir biologiniam poveikiui tyrimai / |
| Translation of Title |
Nanocarriers for red clover extract components transdermal delivery and analysis of biological effect. |
| Authors |
Bernatavičiūtė, Miglė |
| Full Text |
|
| Pages |
55 |
| Keywords [eng] |
Trifolium pratense ; transdermal ; nanocarriers ; UV protection |
| Abstract [eng] |
Red clover (Trifolium pratense L.) is a plant grown all around the world and long time used as a drug in alternative medicine. Extract is a rich source of flavonoids – mainly four major estrogenic isoflavones genistein, daidzein, and their derivatives biochanin A and formononetin. Isoflavones has antimicrobial, anti-inflammatory, antioxidant, anticancer properties and could be used in skin protection from UV radiation oxidative damage. UVB and UVA are two basic types of ultraviolet light that reach the surface of earth and induce main skin diseases. For this reason, red clover extract is one of the potential plant for prevention of skin damage. No scientific data were found regarding red clover extract penetration into the skin. Extract incortoration into the nanocarriers is one of the solution. Niosomes are submicron sized vesicles formed due to self-assembly of one or more nonionic surfactants or lipid. No information were found regarding red clover extract and niosomal formulation effects as an antioxidative agent on the skin and no nanocarrier discribed as a effective vesicle for transdermal red clover extract delivery. |
| Dissertation Institution |
Kauno technologijos universitetas. |
| Type |
Master thesis |
| Language |
Lithuanian |
| Publication date |
2018 |
