| Title |
3D printing and characterization of HA/Mg-reinforced PLA–PHA–PHB composite scaffolds for biomedical applications |
| Authors |
Raziyan, Motahareh Sadat ; Janusas, Giedrius ; Grodzki, Wojciech ; Borucińska-Parfieniuk, Ewa ; Urbaite, Sigita ; Perkowski, Dariusz M |
| DOI |
10.3390/app16083647 |
| Full Text |
|
| Is Part of |
Applied sciences.. Basel : MDPI. 2026, vol. 16, iss. 8, art. no. 3647, p. 1-19.. ISSN 2076-3417 |
| Keywords [eng] |
biopolymers ; hydroxyapatite ; bone-tissue engineering ; bioactive scaffold ; additive manufacture |
| Abstract [eng] |
This research introduces a new hydroxyapatite-based composite, designed as a bone-implant scaffold—easy, quick, economical, and closely mimicking the structure of natural bone. Additive manufacture was used to print bioactive material to form a scaffold structure. Thus, during the experimental research, three different composite materials were made to examine both their mechanical and morphological properties. Numerical modeling was used to maximize and prove the mechanical and biological performance of the HA-polymer grafts. The obtained results indicated that incorporating HA and Mg particles into a polymeric matrix allows the structure to be used in tissue engineering. Best results were obtained using a structure, designed from PLA and PHA at 30%, PHB at 25%, Mg at 5%, and HA at 10%. The composite was distinguished by its lightness, strength, and biocompatibility, making it suitable for tissue engineering. |
| Published |
Basel : MDPI |
| Type |
Journal article |
| Language |
English |
| Publication date |
2026 |
| CC license |
|
