Title Automated segmentation of psoriasis in uncontrolled environments using a three-class ensemble architecture
Authors Audinys, Robertas ; Paskeviciute, Vaiva ; Raudonis, Vidas ; Eidimtas, Linas ; Stragyte, Dominyka ; Valiukeviciene, Skaidra
DOI 10.3390/app16052422
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Is Part of Applied sciences.. Basel : MDPI. 2026, vol. 16, iss. 5, art. no. 2422, p. 1-21.. ISSN 2076-3417
Keywords [eng] psoriasis ; semantic segmentation ; ensemble learning ; medical image analysis ; deep learning ; automated diagnosis
Abstract [eng] Psoriasis is a heterogeneous inflammatory skin disease requiring continuous monitoring to assess treatment efficacy. Automated lesion segmentation remains a significant computer vision challenge due to irregular plaque boundaries, variable skin tones, and uncontrolled lighting conditions in clinical photography. This study proposes a robust hybrid deep learning framework for the automated segmentation of psoriatic lesions in unconstrained environments. We constructed a unique dataset utilizing a hierarchical three-class labeling scheme (psoriatic plaque, healthy skin, and background) to mitigate the class imbalance and background noise often found in binary segmentation tasks. Following a systematic hyperparameter optimization using the Optuna framework, three distinct architectures—DeepLabV3+, UperNet, and SegFormer—were identified as optimal. A novel ensemble architecture was then developed to integrate the high sensitivity of DeepLabV3+, the precision of UperNet, and the contextual balance of SegFormer via a conflict-resolution voting algorithm. Experimental results demonstrate that the proposed hybrid model outperforms individual state-of-the-art architectures, achieving a Dice coefficient of 89.3% for lesion segmentation and an F1 score of 90.7% across skin classes. These findings confirm the system’s adaptability to real-world imaging conditions, validating its potential as an objective decision-support tool for dermatological practice.
Published Basel : MDPI
Type Journal article
Language English
Publication date 2026
CC license CC license description