Title Graphical and statistical analyses of the oculocardiac reflex during a non-invasive intracranial pressure measurement /
Authors Hamarat, Yasin ; Bartusis, Laimonas ; Deimantavicius, Mantas ; Siaudvytyte, Lina ; Januleviciene, Ingrida ; Ragauskas, Arminas ; Bershad, Eric M ; Fandino, Javier ; Kienzler, Jenny ; Remonda, Elke ; Matijosaitis, Vaidas ; Rastenyte, Daiva ; Petrikonis, Kestutis ; Berskiene, Kristina ; Zakelis, Rolandas
DOI 10.1371/journal.pone.0196155
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Is Part of PLoS One.. San Francisco, CA : Public library of science. 2018, vol. 13, iss. 4, art. no. e0196155, p. 1-11.. eISSN 1932-6203
Keywords [eng] oculocardiac reflex ; non-invasive intracranial pressure measurement ; graphical and statistical analyses
Abstract [eng] Purpose. This study aimed to examine the incidence of the oculocardiac reflex during a non-invasive intracranial pressure measurement when gradual external pressure was applied to the orbital tissues and eye. Methods. Patients (n = 101) and healthy volunteers (n = 56) aged 20–75 years who underwent a non-invasive intracranial pressure measurement were included in this retrospective oculocardiac reflex analysis. Prespecified thresholds greater than a 10% or 20% decrease in the heart rate from baseline were used to determine the incidence of the oculocardiac reflex. Results. None of the subjects had a greater than 20% decrease in heart rate from baseline. Four subjects had a greater than 10% decrease in heart rate from baseline, representing 0.9% of the total pressure steps. Three of these subjects were healthy volunteers, and one was a glaucoma patient. Conclusion. The incidence of the oculocardiac reflex during a non-invasive intracranial pressure measurement procedure was very low and not associated with any clinically relevant effects.
Published San Francisco, CA : Public library of science
Type Journal article
Language English
Publication date 2018