Title The Relationship between intracranial pressure and visual field clusters in normal-tension glaucoma patients /
Authors Šiaudvytytė, Lina ; Janulevičienė, Ingrida ; Daveckaitė, Akvilė ; Ragauskas, Arminas ; Harris, Alon
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Is Part of 12th EGS Congress : Prague, Czech Republic, 19-22 June 2016 : abstracts / European Glaucoma Society.. Prague : European Glaucoma Society. 2016, p. 160-160, no. P2.74
Keywords [eng] Low tension glaucoma ; Intracranial pressure ; Visual fields
Abstract [eng] Purpose: To assess relationship between intracranial pressure (ICP) and visual field (VF) clusters in normal-tension glaucoma (NTG) patients. Methods: 80 NTG patients [age 59.5(11.6) years] with minimal VF defects (according to Hodapp-Parrish-Anderson glaucoma grading scale) were included in the prospective study. During the study intraocular pressure (IOP), non-invasive ICP and perimetry were assessed. Non-invasive ICP was measured using two-depth Transcranial Doppler device (Vittamed UAB, Kaunas, Lithuania). VF tests were conducted using the Humphrey 24-2 Swedish interactive thresholding algorithm (SITA) perimeter. The VFs of each patient were divided into five clusters: nasal, temporal, peripheral, central and paracentral. The score for each cluster was the averaged pattern deviation scores of all tested points within the cluster. The level of significance p < 0.05 was considered significant. Results: NTG patients had mean ICP 8.5 (2.4) mmHg, IOP 15.0 (2.3) mmHg, VF defects: nasal -2.5 (2.1) dB, temporal -1.9 (2.1) dB, peripheral -2.3 (1.8) dB, central -1.2 (0.7) dB, paracentral -1.8 (1.0) dB. Lower ICP was related to deeper nasal VF defect (r = 0.36; p = 0.001). There were no significant correlations between ICP and other VF clusters (p > 0.05). NTG patients with deeper nasal VF defects had statistically significantly lower ICP 7.3 (2.1) mmHg, compared to NTG patients with other deeper VF clusters [temporal 9.3 (2.5) mmHg, p = 0.02; peripheral 9.2 (2.7) mmHg, p = 0.02; central 9.9 (2.0) mmHg, p = 0.01; paracentral 9.2 (2.0) mmHg, p = 0.02]. There were no statistically significant differences in IOP between NTG patients with different deeper VF clusters, p = 0.36. Conclusions: NTG patients with deeper nasal VF defects had lower ICP compared to NTG patients with other deeper VF clusters. ICP was positively correlated with nasal VF cluster defects. Further studies are needed to analyze the involvement of ICP in norm [...].
Published Prague : European Glaucoma Society
Type Conference paper
Language English
Publication date 2016