| Title |
Reactions of 9-alkyl-3-aminocarbazoles with ethyl-3-oxo-butanoate and identification of the products obtained |
| Authors |
Sapijanskaite, Birute ; Mickevicius, Vytautas ; Mikulskienė, Gema |
| DOI |
10.3390/11010072 |
| Full Text |
|
| Is Part of |
Molecules.. Basel : MDPI. 2006, vol. 11, iss. 1. ISSN 1420-3049 |
| Keywords [eng] |
Condensation ; Intramolecular cyclization ; Substituted pyrido[2,3-c]carbazol-1-ones ; NMR spectra ; Molecular modeling |
| Abstract [eng] |
The reactions in benzene of 9-alkyl-3-aminocarbazoles with ethyl-3-oxobutanoate yielded ethyl-3-[(9-alkyl-9H-carbazol-3-yl)amino]but-2-enoate condensation products or N- (9-ethyl-9H-carbazol-3-yl)-3-oxobutanamide acylation products. The condensation products were cyclized to the corresponding 4,7-dihydro-pyrido[2,3-c]-carbazol-1-ones upon heating in mineral oil at 240-250 °C. The structures of the synthesized compounds were investigated by IR, mass spectrometry, 1H- and 13C-NMR spectroscopy and MM2 molecular mechanics and AM1 semi-empirical quantum mechanical methods. Keywords: Condensation, intramolecular cyclization, substituted pyrido[2,3-c]carbazol-1-. |
| Published |
Basel : MDPI |
| Type |
Journal article |
| Language |
English |
| Publication date |
2006 |
| CC license |
|
