| Title |
Dosimetric impact of interfractional organ variations in cervical cancer IMRT: a CBCT-based replanning study |
| Authors |
Erkinova, Hilolaknon ; Arslonova, Shirin ; Adliene, Diana ; Musayev, Doniyor ; Polvonov, Satimboy |
| Full Text |
|
| Is Part of |
Medical physics in the Baltic states 2025: proceedings of the 17th international conference on medical physics, 6-8 November 2025, Kaunas, Lithuania / executive editor Diana Adlienė.. Kaunas : Kaunas University of Technology. 2025, p. 37-42.. ISSN 1822-5721 |
| Keywords [eng] |
IMRT ; Cervical cancer ; Interfractional organ motion ; Cone-beam CT ; Replanning |
| Abstract [eng] |
Interfractional variations of bladder and rectum volumes remain a major challenge in cervical cancer IMRT, as small margins make target coverage highly sensitive to anatomical changes. In this work, CBCT-based replanning was performed for ten patients (98 scans) to assess the dosimetric effects of such variations. It was found that CTV coverage decreased significantly (median V98%: 99.5% → 96.4%), while bladder and rectal doses increased with unstable filling patterns. Strong correlations were observed between bladder/rectal changes and dosimetric outcomes. Based on these findings, institutional protocols were developed for regional patient population, standardizing bladder volumes (120–150 cc) and rectal diameters (≤4.5–5.0 cm) to improve treatment consistency. |
| Published |
Kaunas : Kaunas University of Technology |
| Type |
Conference paper |
| Language |
English |
| Publication date |
2025 |
| CC license |
|
