| Abstract [eng] |
Acne vulgarisis a chronic inflammatory disease that develops due to sebum overproduction, follicular hyperkeratinization, and obstruction of skin glands. Patients experience various lesions and skin inflammation, and in severe cases dermal damage or scarring. Treatment of acne vulgaris is mostly based on systemic and topical medications, which often leads to side effects such as skin dryness, irritation and barrier imbalance. Due to poor skin condition, patients may also suffer from social discomfort, anxiety, or even depression. In recent years, a clear increase in consumer interest in sustainable and functional products has been observed in the cosmetics industry. Consequently, manufacturers are developing new types of cosmetic products enriched with natural or plant-derived functional ingredients and are choosing more sustainable production methods and technologies. The object of this study is biodegradable nano/microfiber mats formed by electrospinning, intended for cosmetic applications. The aim of the research is to develop degradable dry sheet face masks for the complex management of acne vulgaris and to evaluate the suitability of these electrospun mats. Using coaxial electrospinning technology, nonwoven mats were fabricated from rabbit collagen and polyvinylpyrrolidone, incorporating bioactive additives (sodium hyaluronate and herbal extracts), selected for their biocompatibility as well as anti-inflammatory, soothing, and moisturizing properties. The work includes analysis of scientific studies related to dry sheet mask fabrication, selection of solution compositions and electrospinning parameters. The influence of composition and process conditions on the structure and chemical properties of the mats was investigated. To evaluate mat properties, physical, chemical, and morphological characterization methods were applied, degradation test and a qualitative assessment of mask behavior on the skin. The social impact of the developed face masks on patients during treatment and the contribution of biodegradable cosmetic face masks to a more sustainable dermatology sector and circular economy were also assessed. It was found that the fabricated dry mats dissolve in water, adapt well to the skin, exhibit a continuous and porous structure, and may potentially be applied in the future to support the management of dermatological problems. |
