| Title |
Synthesis and cyclizations of N-(2,3-, 3,4- and 3,5-dimethylphenyl)-β-alanines / |
| Authors |
Vaickelioniene, Rita ; Mickevicius, Vytautas ; Mikulskiene, Gema |
| DOI |
10.3390/10020407 |
| Full Text |
|
| Is Part of |
Molecules.. Basel : MDPI. 2005, vol. 10, iss. 2, p. 407-416.. ISSN 1420-3049 |
| Keywords [eng] |
N-aryl-β-alanines ; 1-aryl substituted dihydropyrimidinedione |
| Abstract [eng] |
A series of 1-aryl substituted dihydro-, 5-methyldihydro- and 6-methyldihydro- 2,4(1H,3H)pyrimidinediones and their 2-thio analogues were obtained by reaction of the corresponding β-alanines or α-methyl- and β-methyl-β-alanines with urea or potassium thiocyanate. The reaction of N-(2,3- and 3,5-dimethylphenyl)-α-methyl-β- alanines with ethyl acetoacetate gave 1-(2,3- or 3,5-dimethylphenyl)-2,5-dimethyl- 1,4,5,6-tetrahydro-4(1H)pyridones. The combined spectral data obtained by 1H-, 13C-, 1H/13C (HETCOR) NMR and IR provided useful information about the structure of the products synthesized in this work. |
| Published |
Basel : MDPI |
| Type |
Journal article |
| Language |
English |
| Publication date |
2005 |
| CC license |
|
