| Title |
Facile one-pot Fischer–Suzuki–Knoevenagel microwave-assisted synthesis of fluorescent 5-aryl-2-styryl-3H-indoles |
| Authors |
Bartkus, Martynas Rojus ; Kleizienė, Neringa ; Bieliauskas, Aurimas ; Šačkus, Algirdas |
| DOI |
10.3390/molecules30122503 |
| Full Text |
|
| Is Part of |
Molecules.. Basel : MDPI. 2025, vol. 30, iss. 12, art. no. 2503, p. 1-26.. ISSN 1420-3049 |
| Keywords [eng] |
one-pot synthesis ; consecutive multicomponent reaction ; microwave synthesis ; Fischer synthesis ; Suzuki cross-coupling reaction ; Knoevenagel condensation ; 2-styryl-3Hindole ; fluorescence |
| Abstract [eng] |
In this study, novel fluorescent 5-aryl-2-styryl-3H-indole derivatives were efficiently synthesized from 4-bromophenylhydrazine hydrochloride using the microwave-accelerated one-pot technique, which includes Fischer synthesis, Suzuki cross-coupling, and Knoevenagel condensation. The structural assignments of the synthesized compounds were based on 1H, 13C, 15N, and 19F NMR; IR spectroscopy; and HRMS spectral data. The optical properties of the newly obtained styryl-indole dyes were studied using UV-vis and fluorescence spectroscopy, which clearly demonstrated that the derivatives substituted with electron-donating or -withdrawing groups exhibited varying emission shifts and quantum yields ranging from negligible to high. |
| Published |
Basel : MDPI |
| Type |
Journal article |
| Language |
English |
| Publication date |
2025 |
| CC license |
|
