Title Hidrazonų iš 3-[(4-etoksifenil)amino]propanhidrazido sintezė, charakterizacija ir biologinio aktyvumo vertinimas
Translation of Title Synthesis, characterization, and biological activity evaluation of hydrazones from 3-[(4-ethoxyphenyl)amino]propanehydrazide.
Authors Kiltinavičius, Juozas
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Pages 72
Keywords [eng] hydrazide ; hydrazones ; condensation reactions ; antioxidant activity ; antibacterial activity
Abstract [eng] In this work, new hydrazones were synthesised from the starting hydrazide and various substituted aromatic ketones and aldehydes. The starting material 3-[(4-ethoxyphenyl)amino]propanehydrazide was synthesised in two steps from 4-ethoxyaniline and methyl acrylate by treatment of the resulting intermediate ester with hydrazine hydrate. Reactions of 3-[(4-ethoxyphenyl)amino]propanehydrazide with substituted ketones and aldehydes bearing various heterocyclic moieties and functional groups in their structure were carried out, leading to different biological activity of the obtained products.
Dissertation Institution Kauno technologijos universitetas.
Type Master thesis
Language Lithuanian
Publication date 2025