| Title |
Wound dressings films based on the citric acid modified starch |
| Authors |
Ishchenko, Olena ; Kuchynska, Daria ; Plavan, Viktoriia ; Ostrauskaitė, Jolita |
| DOI |
10.2478/9788367405805-014 |
| ISBN |
9788367405805 |
| Full Text |
|
| Is Part of |
ICAMS 2024: proceedings of the 10th international conference on advanced materials and systems, 30-31 October 2024, Bucharest, Romania / L. Alexandrescu, D. Gurău (eds.).. Warsaw : Sciendo, 2024. p. 101-106.. ISSN 2068-0783. ISBN 9788367405805 |
| Keywords [eng] |
citric acid ; modified starch ; wound dressings |
| Abstract [eng] |
The research focuses on obtaining polymer films based on citric acid-modified starch (MSt) in combination with polyvinyl alcohol (PVA) as a base for wound dressings with prolonged drug release. Starch modification was carried out with 0.5 and 1 mol/l citric acid solutions at a temperature of 40°C for 1.5, 2.0 and 2.5 hours. 10% solutions of MSt and PVA were mixed in ratios of 25:75, 50:50 and 75:25 to obtain films by the solution casting method. The influence of citric acid concentration and processing time on the physical-mechanical properties of the films was studied using an automated tensile testing machine ZwickRoell Z2.5TH1. The peculiarities of the interaction between PVA and MSt at different modification durations were determined by Fourier-transform infrared spectroscopy. It was established that the duration of modification and the concentration of citric acid affect the physical mechanical properties of the films. It was found that increasing the concentration of citric acid contributes to obtaining stronger films. The duration of starch modification with citric acid does not significantly affect the sorption properties of the films, which were evaluated by the amount of water vapor sorption. The sorption properties of the films largely depend on the ratio of MSt and PVA. Thus, films with an MSt/PVA ratio of 75:25 demonstrate an optimal set of properties. The obtained films can be a base for wound dressings with prolonged drug release. |
| Published |
Warsaw : Sciendo, 2024 |
| Type |
Conference paper |
| Language |
English |
| Publication date |
2024 |
| CC license |
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