Title Kolateralinės kraujotakos smegenyse modelių sudarymas /
Translation of Title Creating models of collateral circulation in the brain.
Authors Rastenis, Tomas
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Pages 43
Keywords [eng] collateral circulation ; Starling resistor ; ischemic stroke
Abstract [eng] Brain circulation confusion (stroke) is in the third place of disablement cause in Lithuania: 1. Injury diseases; 2. Oncological deseases; 3. Strokes; Mortality of strokes are about 30 – 40 percents of patients. Organism ability to give blood flow through the secondary ways in the tissues and cells, which don‘t get necessary blood flow (or don‘t got any blood flow), when main veins are in occlusion, calls collateral circulation. Colletarel circulation is very important blood autoregulation process. It‘s able reduce or completely remove results of stroke, but generally collateral circulation don‘t work properly. We used electrical circuits theory to create collateral circulation models, which simulates collateral circulation in partial occlusion and in complete occlusion. We determined electrical circuits equivalence to define blood flow in the brain.We found when veins of ischemic region press up and blood flow stops and venous blood flow out from ischemic region when venous presure raises. We sets requirements what to do in stroke time, that violations for brain tissue to minimal. In the event of breach of stroke brain tissue, it swells up after the damage as the water passes into the tissues, thus increasing the external tissue pressure. The object of this work - to create the current redistribution of blood flow during the stroke, dependent on the venous pressure in the blood vessels surrounding tissues to different pressures. The development of collateral blood flow patterns in close co-operation and consultation with the New York Queen's Hospital anaesthesiologists Osvaldas Pranevicius and Albert Einstein College of Medicine Head of Anesthesiology Mindaugas Pranevicius.
Type Master thesis
Language Lithuanian
Publication date 2012