| Title |
Ląstelių plyšinių jungčių Markovo modelio sudarymo sistema / |
| Translation of Title |
Markovian model generator for cell gap junction channels. |
| Authors |
Bazaras, Edvinas |
| Full Text |
|
| Pages |
55 |
| Keywords [eng] |
CGJ ; connexin ; Markov model ; fuzzy logic ; GPU |
| Abstract [eng] |
The major goal of this study was to prove that continuous time Markov models of voltage gating of gap junction (GJ) channels is faster and better way to make digital models of connexin protein. This goal was achieved by using created software that models connexin gating voltage graphs in real time. Created software is capable of modeling two types of voltage graphs: stochastic and deterministic. To avoid using piece linear aggregates (PLA) formalism, these models were implemented strictly on object oriented programming paradigm by dividing system into object that can be fully described by classes in any programming language. Developed Markov models were used to investigate the evolution of gap junctional conductance depending on trans-junctional voltage. |
| Type |
Master thesis |
| Language |
Lithuanian |
| Publication date |
2013 |
