| Title |
Functionalisation of graphene/graphene oxide and the application of it and its derivatives in nanomedicine / |
| Translation of Title |
Grafeno / grafeno oksido funkcionalizavimas ir jo bei jo darinių taikymas nanomedicinoje. |
| Authors |
Šlekienė, Nora |
| Full Text |
|
| Pages |
133 |
| Keywords [eng] |
graphene / graphene oxide ; functionalization ; toxicity of nanoparticles ; lipid membranes |
| Abstract [eng] |
During this study, the new graphene-based hybrid nanostructures with porphyrins were synthesised. The interaction of nanoparticles with lipid membranes was performed, the impact of graphene oxide and functionalized graphene oxide on the viability of different cell lines (Chinese hamster ovary and mouse hepatoma MH-22A cells) were evaluated. It was found, that the cancerous cells are better at absorbing graphene oxide nanoparticles than healthy cells and the functionalisation of GO with doxorubicin enhances the anticancer effect of doxorubicin. |
| Dissertation Institution |
Kauno technologijos universitetas. |
| Type |
Doctoral thesis |
| Language |
English |
| Publication date |
2017 |
