| Abstract [eng] |
Various nanostructured membranes attract immense attention because they are characterized by versatility, stability, and the ability to control the parameters, which leads to the creation of unique structures. Recently, a breakthrough has been observed in a number of fields of bioengineering, where nanostructured membranes were practically applied in bone and skin tissue engineering and drug delivery systems. In terms of mechanical engineering, there is still a lack of knowledge on the mechanical strength and biocompatibility of nanostructured membranes. As the relationship between the mechanical strength and biocompatibility of nanostructured membranes depends on the material and the fabrication method, it is relevant to choose the right technology to produce these membranes and apply them commercially. When designing synthetic nanostructured membranes, it is also important to ensure an ordered internal structure, which determines the unique properties of each membrane. This doctoral dissertation presents a novel fabrication technology of nanoporous AAO membranes using vibrations, including production processes, their parameters, and a description of the properties of the fabricated membranes. Moreover, the doctoral dissertation presents a technology for replicating the geometry of the AAO membrane in a biocompatible chitosan membrane, when nanopillars are formed on the surface of the chitosan membrane. It also presents the relationships and interactions studied between various parameters, which is achieved by presenting sets of experimental results. |
