| Title |
Oxygen saturation increase in ischemic wound tissues after direct and indirect revascularization / |
| Authors |
Račytė, Austėja ; Pikturnaitė, Gabija ; Baltrūnas, Tomas ; Kalvaitis, Evaldas ; Vaitėnas, Gediminas ; Skrebūnas, Arminas ; Baltrūnienė, Vaida ; Ručinskas, Kęstutis |
| DOI |
10.3390/biomedicines12020367 |
| Full Text |
|
| Is Part of |
Biomedicines.. Basel : MDPI. 2024, vol. 12, iss. 2, art. no. 367, p. 1-10.. ISSN 2227-9059 |
| Keywords [eng] |
angiosome ; chronic limb-threatening ischemia ; chronic total occlusion ; direct revascularization ; indirect revascularization ; ischemic wounds ; near-infrared spectroscopy |
| Abstract [eng] |
BACKGROUND: The primary approach for treating ischemic wounds is restoring oxygen supply to the ischemic region. While direct angiosomal revascularization is often associated with better post-operative wound healing and limb salvage, its superiority over non-angiosomal revascularization remains controversial. This study aimed to compare intraoperative tissue oxygen saturation changes in ischemic zones following either direct or indirect revascularization in below-the-knee arteries. METHODS: This prospective observational study included patients undergoing direct and indirect below-the-knee endovascular revascularizations. Assignment to the groups was not randomized. Near-infrared spectroscopy was used to monitor rSO2 changes near the ischemic wounds intraoperatively. The changes were compared between the groups. RESULTS: 15 patients (50%) underwent direct angiosomal revascularization, while an equal number of patients underwent indirect revascularization. Overall, a statistically significant increase in regional oxygen saturation was observed after revascularization (p = 0.001). No statistically significant difference was found between the direct and indirect revascularization groups (p = 0.619). CONCLUSIONS: This study revealed a minor difference in the oxygen saturation increase between the angiosomal and non-angiosomal revascularization groups. Such a finding indicates that the clinical significance of angiosomal revascularization is negligible and might be concealed by confounding factors, such as the vessel diameter and outflow impact on the restenosis rate. |
| Published |
Basel : MDPI |
| Type |
Journal article |
| Language |
English |
| Publication date |
2024 |
| CC license |
|
