Title Tarpląstelinių plyšinių jungčių imitacinio modelio kūrimas ir tyrimas /
Translation of Title Intercellular gap junction imitation model cretion and research.
Authors Paulauskas, Nerijus
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Pages 70
Keywords [eng] intercellular gap junctions ; imitation model ; programming language
Abstract [eng] The work describes gap junction model imitation system formally known as the GJM (Gap Junction Model). In this system created simulation models simulates electrophysiological processes in gap junction channels. The work presents gap junction models with different formal gap junction channels specifications. Created formal models have been used in the creation of gap junction model imitation system. The system was developed using C # programming language. System was developed in groups of interfaces allowing passing gap junction model parameters and voltage excitations to different types of gap junction channels Formulated global optimization problem for the simulation results which allows approximate imitation data to experimental data obtained from the New York, Yeshiva University, Albert Einstein College of Medicine Laboratory. There are presented the results of simulation models and their comparisons with the results of experiments with different types of channels.
Type Master thesis
Language Lithuanian
Publication date 2009