| Title |
DLC:CU thin film stability testing in cell culture medium / |
| Authors |
Elkhider, Shahd ; Baba, Mohamed A ; Vasiliauskas, Andrius ; Meškinis, Šarūnas ; Zienius, Dainius ; Lelešius, Raimundas ; Šalomskas, Algirdas ; Tamulevičius, Tomas |
| DOI |
10.15388/IOR2023 |
| ISBN |
9786090708835 |
| Full Text |
|
| Is Part of |
Open readings 2023: 66th international conference for students of physics and natural sciences, April 18-21, 2023, Vilnius, Lithuania: annual abstract book / editors: M. Keršys, Š. Mickus.. Vilnius : Vilnius University press, 2023. p. 64.. ISBN 9786090708835 |
| Abstract [eng] |
different properties from the bulk material in size reduction and high surface area [1, 2]. Copper (Cu) nanoparticles were found to have antiviral properties against a range of viruses [3]. The nanoparticle can increase the drug solubility in water and the drug uptake by the infected cell which can increase the biomedical application in drug delivery systems [4]. In this work, the amorphous diamond-like carbon thin films with Cu nanoparticles (DLC:Cu) were deposited on crystalline silicon substrates by reactive magnetron sputtering of a metal target in an acetylene gas atmosphere. The nanocomposite DLC:Cu films are intended for antiviral effect testing by cell culture method. The DLC:Cu film stability was tested using culture media Dulbecco's Modified Eagle's Medium (DMEM) for a different set of time durations (5 and 10 minutes). The sample changed color from metallic copper to green which was confirmed by the UV–visible spectrophotometry measurements (Fig.1). The initial results suggest that copper nanoparticles are oxidized. Copper oxidation, ion, and nanoparticle release in the medium are important for DLC:Cu application for antimicrobial and antiviral applications. [...]. |
| Published |
Vilnius : Vilnius University press, 2023 |
| Type |
Conference paper |
| Language |
English |
| Publication date |
2023 |
| CC license |
|
