| Title |
Synthesis of chitosan-graft-poly(N-isopropylacrylamide) copolymers / |
| Authors |
Navikaite-Snipaitiene, V ; Kairyte, A ; Babelyte, M ; Peciulyte, L ; Rutkaite, R ; Samaryk, V |
| DOI |
10.15388/CCT.2023 |
| ISBN |
9786090708330 |
| Full Text |
|
| Is Part of |
Chemistry and chemical technology: international conference CCT-2023, March 10, 2023, Vilnius: conference book.. Vilnius : Vilnius university press, 2023. P 055, p. 92.. ISBN 9786090708330 |
| Abstract [eng] |
Poly(N-isopropylacrylamide) is one of the most popular thermo-responsive synthetic polymers that exhibits dramatic and reversible phase transition behavior in water [1]. Recently, copolymers with grafted poly(Nisopropylacrylamide) side chains are highly researched, particularly, in terms of drug delivery and biomedical applications. By using such synthesis strategy thermoresponsive polymers with biocompatible polysaccharide e.g. chitosan main chain and synthetic side chains, and dual (pH and temperature) responsive properties can be obtained [2]. The aim of this study was to prepare chitosan-graft-poly(N-isopropylacrylamide) copolymers using different molar ratios of chitosan (CH) to N-isopropylacrylamide (NIPAA) (see Fig. 1). The synthesis of copolymers was carried out in aqueous solution using potassium persulfate as an initiator at 60 °C temperature under a nitrogen atmosphere. After the reaction, the products were precipitated into acetone and obtained copolymers were purified by using methanol. The molar ratio of CH to NIPAA in the polymerization mixture was varied from 1:0.25 to 1:10. [...]. |
| Published |
Vilnius : Vilnius university press, 2023 |
| Type |
Conference paper |
| Language |
English |
| Publication date |
2023 |
| CC license |
|
