| Title |
Synthesis of N-[3-(Hydrazinecarbonyl)-4-hydroxyphenyl]acetamide Derivatives / |
| Authors |
Špiliauskas, V ; Anusevičius, K ; Grybaitė, B ; Jonuškienė, I ; Sapijanskaitė-Banevič, B ; Vaickelionienė, R ; Mickevičius, V |
| DOI |
10.15388/CCT.2023 |
| ISBN |
9786090708330 |
| Full Text |
|
| Is Part of |
Chemistry and chemical technology: international conference CCT-2023, March 10, 2023, Vilnius: conference book.. Vilnius : Vilnius university press, 2023. P 002, p. 39.. ISBN 9786090708330 |
| Abstract [eng] |
Mesalazine is also known as 5-aminosalicylic acid and used to treat inflammatory bowel disease. However, 5- aminosalicylic carbohydrazyde was studied as a promising scaffold with antibacterial properties [1]. In this work N-[3-(hydrazinecarbonyl)-4-hydroxyphenyl]acetamide (1) was synthesized by the method described in article [2]. Developing of compounds with antibacterial properties are involved to synthesis of 1,3,4-oxadiazole [3], 4- amino-1,2,4-triazole [4], triazolothiadiazine [5] or certain Schiff base [6] moiety. Bearing in mind these properties, we proceeded with modification of the 5-aminosalicylic carbohydrazide 1 following scheme 1. [...]. |
| Published |
Vilnius : Vilnius university press, 2023 |
| Type |
Conference paper |
| Language |
English |
| Publication date |
2023 |
| CC license |
|
