| Title |
Synthesis and antibacterial and antifungal activity of N-(4-fluorophenyl)-N-carboxyethylaminothiazole derivatives / |
| Authors |
Vaickelionienė, Rita ; Mickevičius, Vytautas ; Vaickelionis, Giedrius ; Stasevych, Maryna ; Komarovska-Porokhnyavets, Olena ; Novikov, Volodymyr |
| DOI |
10.3998/ark.5550190.p009.170 |
| Full Text |
|
| Is Part of |
Arkivoc.. Gainesville, FL : Arkat. 2015, vol. 2015, iss. 5, p. 303-318.. ISSN 1551-7004. eISSN 1551-7012 |
| Keywords [eng] |
amino acids ; aminothiazoles ; Hantzsch reaction ; condensation ; chalcones ; antimicrobial agents |
| Abstract [eng] |
A series of novel N-(4-fluorophenyl)-N-carboxyethylaminothiazoles and thiazolones with aliphatic, aromatic and heterocyclic substituents were obtained in good to excellent overall yields. The synthesized compounds were screened for their antimicrobial and antifungal activity. The antibacterial tests indicated that the functionalized aminothiazole derivatives exhibit a higher activity as compared with thiazolone derivatives. |
| Published |
Gainesville, FL : Arkat |
| Type |
Journal article |
| Language |
English |
| Publication date |
2015 |
| CC license |
|
