Title |
The relationship between intracranial pressure and visual field zones in normal-tension glaucoma patients / |
Authors |
Stoskuviene, Akvile ; Siaudvytyte, Lina ; Januleviciene, Ingrida ; Vaitkus, Antanas ; Simiene, Evelina ; Bakstyte, Viktorija ; Ragauskas, Arminas ; Antman, Gal ; Siesky, Brent ; Harris, Alon |
DOI |
10.3390/diagnostics13020174 |
Full Text |
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Is Part of |
Diagnostics.. Basel : MDPI. 2023, vol. 13, iss. 2, art. no. 174, p. 1-10.. ISSN 2075-4418 |
Keywords [eng] |
normal-tension glaucoma ; intracranial pressure ; translaminar pressure difference ; visual field zones |
Abstract [eng] |
Growing evidence suggests that intracranial pressure (ICP) plays an important role in the pathophysiology of glaucoma, especially in normal-tension glaucoma (NTG) patients. Controversial results exist about ICP’s relationship to visual field (VF) changes. With the aim to assess the relationship between ICP and VF zones in NTG patients, 80 NTG patients (age 59.5 (11.6) years) with early-stage glaucoma were included in this prospective study. Intraocular pressure (IOP) (Goldmann), visual perimetry (Humphrey) and non-invasive ICP (via a two-depth Transcranial Doppler, Vittamed UAB, Lithuania) were evaluated. Translaminar pressure difference (TPD) was calculated according to the formula TPD = IOP − ICP. The VFs of each patient were divided into five zones: nasal, temporal, peripheral, central, and paracentral. The average pattern deviation (PD) scores were calculated in each zone. The level of significance p 0.05). Further studies are needed to analyze the involvement of ICP in NTG management. |
Published |
Basel : MDPI |
Type |
Journal article |
Language |
English |
Publication date |
2023 |
CC license |
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