| Title |
Cyanide anion determination based on nucleophilic addition to 6-[(E)-(4-nitrophenyl)diazenyl]-1',3,3',4-tetrahydrospiro[chromene-2,2'-indole] Derivatives / |
| Authors |
Dagilienė, Miglė ; Markuckaitė, Giedrė ; Krikštolaitytė, Sonata ; Šačkus, Algirdas ; Martynaitis, Vytas |
| DOI |
10.3390/chemosensors10050185 |
| Full Text |
|
| Is Part of |
Chemosensors.. Basel : MDPI. 2022, vol. 10, iss. 5, art. no. 185, p. 1-12.. ISSN 2227-9040 |
| Keywords [eng] |
spiro[chroman-2,2 '-indole] ; cyanide determination ; colorimetry |
| Abstract [eng] |
This work provides a novel approach for the instant detection of CN− anions based on chromogenic 6-[(E)-(4-nitrophenyl)diazenyl]-1′,3,3′,4-tetrahydrospiro[chromene-2,2′-indole] derivatives. New colorimetric detectors were synthesized and characterized. These compounds exhibited a substantial color change from orange to magenta and blue when treated with cyanide ions in a CH3CN solution buffered with sodium phosphate and demonstrated high selectivity to CN− anions. Common anions were tested, and they did not interfere with cyanide detection, except for carbonates and hydrosulfites. The simple preparation of a molecular sensor and the easily noticeable color change makes this a practical system for the monitoring of CN− ions. This color change is explained by nucleophilic substitution of the pyrane ring oxygen atom at the indoline C-2 atom by the cyanide anion. This generates the appearance of intensively colored 4-(4-nitrophenylazo)phenolate chromophore and allows for determining very low levels of CN− anion. |
| Published |
Basel : MDPI |
| Type |
Journal article |
| Language |
English |
| Publication date |
2022 |
| CC license |
|
