| Title |
Evaluation of the absorbed dose in blood samples using the dicentric chromosome assay / |
| Translation of Title |
Sugertosios dozės vertinimas kraujo bandiniuose naudojant dicentrinių chromosomų tyrimo metodą. |
| Authors |
Lileikytė, Lijana |
| Full Text |
|
| Pages |
61 |
| Keywords [eng] |
cytogenetic analysis ; biological dosimetry ; dicentric chromosome assay ; individual radiosensitivity |
| Abstract [eng] |
Cytogenetic analysis can be used to determine both the absorbed dose and the individual radiosensitivity. Sensitivity to ionizing radiation can be an important indicator in providing protection against unjustified exposure and in predicting side effects that occur after radiotherapy treatment or a radiological accident. Cytogenetic analysis for the comparison of evaluated doses using Dicentric Chromosome Assay for the prostate cancer patients has been performed with the aim to identify the difference between Dicentric Chromosome Assay results depending on estimated individual radiosensitivity by using the G2-assay. Six prostate cancer patients who received a total dose of 62–74 Gy were investigated. The blood samples – prior to radiotherapy treatment (2 Gy in vitro) and after completing radiotherapy treatment (in vivo) – were analyzed by the Dicentric Chromosome Assay and using G2-assay. |
| Dissertation Institution |
Kauno technologijos universitetas. |
| Type |
Master thesis |
| Language |
English |
| Publication date |
2022 |
