| Title |
Kolageno dangos iš gyvulinės kilmės atliekų kūrimas ir panaudojimas medicininei tvarsliavai gauti / |
| Translation of Title |
Development and application of collagen coating from animal waste for the production of medical dressing. |
| Authors |
Sinkevičiūtė, Joana |
| Full Text |
|
| Pages |
50 |
| Keywords [eng] |
electrospinning ; nanofibers ; polyvinyl butyral ; polyvinylpyrrolidone ; gelatin |
| Abstract [eng] |
Wounds that are not treated in time or treated improperly are a huge problem in the modern world. Successful wound treatment can be achieved through the use of advanced technologies aimed at producing value-added materials that promote tissue regeneration. One such technology is electrospinning, which uses polymer solutions to form materials that can promote wound healing and protect wounds from potential infections. In order to exploit the advantages of some polymers and overcome the disadvantages of others, increasing attention is being paid to the combination of different polymers, leading to the search for alternatives that improve the biological, physical and chemical properties of the dressings. The final project aims to develop coatings for gelatin derived from animal waste and to investigate their application in medical dressings. The study involved the formation of nano-microfibers of polyvinylpyrrolidone (PVP) and polyvinyl butyral (PVB) with a gelatin coating by electrospinning and the investigation of their structure and properties. It was found that the voltage applied during the forming process influences their diameter size distribution. The influence of a low cytotoxicity extract of common comfrey on the morphology of PVB and PVP coatings was also investigated. It was found that the addition of the extract of common comfrey root to the polymers and gelatin resulted in the formation of continuous coatings of gelatin droplets of uniform diameter on the surfaces. The cost of production of a non-woven fabric formed from such nano-microfibers was calculated. Research project “Technology for Obtaining an Innovative Antimicrobial, Non-active Medical Dressing Through the use of Indigenous Bioresources (NonActivPans)” is funded by the European Regional Development Fund according to the 2014–2020 Operational Programme for the European Union Funds’ Investments under measure No. 01.2.2-MITA-K-702 “Promoting the Commercialisation and Internationalisation of R&D”. |
| Dissertation Institution |
Kauno technologijos universitetas. |
| Type |
Master thesis |
| Language |
Lithuanian |
| Publication date |
2022 |
